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Most not too long ago, it's been discovered that conolidine and the above derivatives act to the atypical chemokine receptor three (ACKR3. Expressed in very similar regions as classical opioid receptors, it binds into a big range of endogenous opioids. Compared with most opioid receptors, this receptor acts as being a scavenger and would not activa

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Most just lately, it has been identified that conolidine and the above derivatives act around the atypical chemokine receptor 3 (ACKR3. Expressed in identical areas as classical opioid receptors, it binds to a big range of endogenous opioids. Not like most opioid receptors, this receptor acts being a scavenger and won't activate a second messenger

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